化工社化工社 化学情報印刷レポート · 研究参考用
Triethylamine → Dimethyl 3(4-nitrophenyl)-2-isoxazolin-5-ylphosphonate
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Triethylamine | HCID 8471 | — |
| 反応物 | Chlorosuccinimide | HCID 31398 | — |
| 反応物 | Dimethyl vinylphosphonate | HCID 78376 | — |
| 反応物 | p-Nitrobenzaldoxime | HCID 96339 | — |
| 生成物 | Dimethyl 3(4-nitrophenyl)-2-isoxazolin-5-ylphosphonate | HCID 14460583 | — |
反応手順
Preparation is carried out in analogy to Example 1 from 19.6 g (0.118 mol) of 4-nitrobenzaldoxime, 17.4 g (0.13 mol) of N-chlorosuccinimide, 16.1 g (0.118 mol) of dimethyl vinylphosphonate and 18.7 ml (0.13 mol) of triethylamine. Crystallization of the crude product from tert.butyl methyl ether provides analytically pure compound of melting point 156° to 158° C.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US05006515 |
| 出典データセット | uspto-grants-1991_04 |
| ORD ID | ord-86704c721ee24713a97ac5b14f74ef72 |
| 出典メモ | uspto-grants-1991_04 |