化工社化工社 化学情報印刷レポート · 研究参考用
1,3-Isobenzofurandione, 5-fluoro- → Methyl 3-(5-fluoro-1,3-dioxo-1,3-dihydro-isoindol-2-yl)-2-(2-methyl-[1,3]dioxolan-2-yl)propionate
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 1,3-Isobenzofurandione, 5-fluoro- | HCID 67572 | — |
| 反応物 | Methyl 3-amino-2-(2-methyl-[1,3]dioxolan-2-yl)propionate | HCID 21982209 | — |
| 生成物 | Methyl 3-(5-fluoro-1,3-dioxo-1,3-dihydro-isoindol-2-yl)-2-(2-methyl-[1,3]dioxolan-2-yl)propionate | HCID 21982231 | — |
反応手順
Methyl 3-(5-fluoro-1,3-dioxo-1,3-dihydro-isoindol-2-yl)-2-(2-methyl-[1,3]dioxolan-2-yl)propionate was prepared (0.66 g, 47%) in the same manner as described in the above example 5 (1) from methyl 3-amino-2-(2-methyl-[1,3]dioxolan-2-yl)propionate (0.80 g, 5.07 mmol) and 4-fluorophthalic anhydride (0.80 g, 5.07 mmol), and the obtained product was identified with the following NMR data.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US07094908B2 |
| 出典データセット | uspto-grants-2006_08 |
| ORD ID | ord-128369000365468e8ac4191f5ff6d728 |
| 出典メモ | uspto-grants-2006_08 |