Hydrochloric Acid → HCID 20062840、化合物

HRID 1084958

反応式

HRID 1084958 の反応式
Br[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][O:7][CH2:8][CH2:9][C:10]1[CH:15]=[CH:14][C:13]([F:16])=[CH:12][CH:11]=1.[CH2:17]([NH2:24])[C:18]1[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=1.[ClH:25]>O>[ClH:25].[F:16][C:13]1[CH:14]=[CH:15][C:10]([CH2:9][CH2:8][O:7][CH2:6][CH2:5][CH2:4][CH2:3][CH2:2][NH:24][CH2:17][C:18]2[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=2)=[CH:11][CH:12]=1

参加物

5

反応物 3

HCID 313Hydrochloric AcidHCID 7504BenzylamineHCID 197980301-[2-[(5-Bromopentyl)oxy]ethyl]-4-fluorobenzene

生成物 1

HCID 20062840HCID 20062840、化合物

試薬・触媒・溶媒 1

HCID 962Water溶媒

実験手順

1-[2-[(5-Bromopentyl)oxy]ethyl]-4-fluorobenzene (7.95 g) was added dropwise over 10 min to benzylamine (24 ml) at 125° under nitrogen. The reaction mixture was stirred for 3.5 h at 120° and the hot reaction mixture was poured into 2N aqueous hydrochloric acid (170 ml) and water (220 ml). After stirring for 15 min the precipitate was collected by filtration to give the title compound as a white solid (7.41 g) m.p. 112°.

後処理

  1. stirringAfter stirring for 15 min the precipitate
  2. filtrationwas collected by filtration

出典と根拠

ORDレコード
ord-739e1043029d4258b88614d783964259
出典データセット
uspto-grants-1991_04
特許番号
US05006556

関連ノート

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