3,5-Dimethylbenzoyl Chloride → HCID 14366285、化合物

HRID 1085364ノート

反応式

HRID 1085364 の反応式
[CH3:1][C:2]1[CH:3]=[C:4]([CH:8]=[C:9]([CH3:11])[CH:10]=1)[C:5](Cl)=[O:6].C[O:13][P:14]1[C:19]2[CH:20]=[CH:21][CH:22]=[CH:23][C:18]=2[C:17]2[CH:24]=[CH:25][CH:26]=[CH:27][C:16]=2[O:15]1>CC(C)=O>[CH3:1][C:2]1[CH:3]=[C:4]([CH:8]=[C:9]([CH3:11])[CH:10]=1)[C:5]([P:14]1(=[O:13])[C:19]2[CH:20]=[CH:21][CH:22]=[CH:23][C:18]=2[C:17]2[CH:24]=[CH:25][CH:26]=[CH:27][C:16]=2[O:15]1)=[O:6]

参加物

4

反応物 2

HCID 810883,5-Dimethylbenzoyl ChlorideHCID 114361486-methoxy-(6H)-dibenz[c,e][1,2]-oxaphosphorin

生成物 1

HCID 14366285HCID 14366285、化合物

試薬・触媒・溶媒 1

HCID 180Acetone溶媒

反応条件

温度
115 °C

実験手順

67.4 g (0.4 mol) of 3,5-dimethylbenzoyl chloride were warmed to 80° C. under a nitrogen atmosphere. 92 g (0.4 mol) of 6-methoxy-(6H)-dibenz[c,e][1,2]oxaphosphorin were added dropwise while stirring. The temperature during the addition was increased in steps to 115° C. When the reaction was complete, 50 ml of acetone were added at room temperature. After crystallization, 113 g (81% of theory) of the abovementioned compound of melting point 120° to 124° C. were obtained.

後処理

  1. additionThe temperature during the addition
  2. customAfter crystallization, 113 g (81% of theory) of the abovementioned compound of melting point 120° to 124° C.
  3. customwere obtained

出典と根拠

ORDレコード
ord-909d4e16ecf84701bb764513ffb2bc94
出典データセット
uspto-grants-1991_04
特許番号
US05008426

反応ノート

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