Triethylamine → HCID 14719431、化合物

HRID 1085375

反応式

HRID 1085375 の反応式
[CH2:1]([O:19][CH2:20][CH2:21][CH2:22][OH:23])[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH3:18].[CH3:24][S:25](Cl)(=[O:27])=[O:26].C(N(CC)CC)C>ClCCl>[CH3:24][S:25]([O:23][CH2:22][CH2:21][CH2:20][O:19][CH2:1][CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH3:18])(=[O:27])=[O:26]

参加物

5

反応物 3

HCID 8471TriethylamineHCID 31297Methanesulfonyl chlorideHCID 5553033-Octadecyloxypropanol

生成物 1

HCID 14719431HCID 14719431、化合物収率 98%

試薬・触媒・溶媒 1

HCID 6344Dichloromethane溶媒

実験手順

In dichloromethane (50 ml) is dissolved 3-(octadecyloxy)propanol (8.0 g). To the solution are added, under ice-cooling, methanesulfonyl chloride (4.18 g) and triethylamine (5.1 ml). The mixture is stirred at room temperature for one hour. The reaction mixture is washed with water and an aqueous solution of sodium hydrogencarbonate, successively, and then dried. The solvent is distilled off under reduced pressure to give the above-titled compound (9.7 g).

後処理

  1. additionTo the solution are added, under ice-
  2. temperaturecooling
  3. washThe reaction mixture is washed with water
  4. dry with materialan aqueous solution of sodium hydrogencarbonate, successively, and then dried
  5. distillationThe solvent is distilled off under reduced pressure

出典と根拠

ORDレコード
ord-5231a62ac23d4fbd8898c56889ce6997
出典データセット
uspto-grants-1991_04
特許番号
US05008454

関連ノート

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