Ethanol → Benzoic acid [1-(4-pyridinyl)ethylidene]hydrazide 1-oxide

HRID 1085937

反応式

HRID 1085937 の反応式
[C:1]([C:4]1[CH:9]=[CH:8][N+:7]([O-])=[CH:6][CH:5]=1)(=O)[CH3:2].[C:11]([NH:19][NH2:20])(=[O:18])[C:12]1[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=1.C([OH:23])C>>[N:7]1[CH:8]=[CH:9][C:4]([C:1](=[N:20][NH+:19]([O-:23])[C:11](=[O:18])[C:12]2[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=2)[CH3:2])=[CH:5][CH:6]=1

参加物

4

反応物 3

HCID 702EthanolHCID 11955BenzoylhydrazineHCID 3375424-Acetylpyridine-N-oxide

生成物 1

HCID 131716837Benzoic acid [1-(4-pyridinyl)ethylidene]hydrazide 1-oxide収率 77%

実験手順

A mixture of 5.48 gm (0.04 mole) of 4-acetylpyridine 1-oxide, 5.45 gm (0.04 mole) of benzhydrazide and 100 ml of absolute ethanol is refluxed for a total of 4 hr and cooled. The reaction mixture is evaporated in vacuo to yield a solid which is crystallized from ethanol to yield 7.82 gm (77%) of the title compound having a melting point of 248.9° C. (decomp).

後処理

  1. temperatureis refluxed for a total of 4 hr
  2. temperaturecooled
  3. customThe reaction mixture is evaporated in vacuo
  4. customto yield a solid which
  5. customis crystallized from ethanol

出典と根拠

ORDレコード
ord-6cd9bb23486d46f49bcbb94130bd8fcd
出典データセット
uspto-grants-1991_04
特許番号
US05011932

関連ノート

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