Stannous Chloride → 2-Chloro-5-hydrazinylbenzoic acid hydrochloride
反応式
[N:1]([O-])=O.[Na+].[NH2:5][C:6]1[CH:7]=[CH:8][C:9]([Cl:15])=[C:10]([CH:14]=1)[C:11]([OH:13])=[O:12].Cl[Sn]Cl>O.Cl>[ClH:15].[NH:5]([C:6]1[CH:7]=[CH:8][C:9]([Cl:15])=[C:10]([CH:14]=1)[C:11]([OH:13])=[O:12])[NH2:1]参加物
6
反応条件
- 温度
- -3 °C
実験手順
A solution of 2.11 g of NaNO2 in 40 ml of water is added over 30 minutes to a suspension, cooled to -2° C., of 5 g of 5-amino-2-chlorobenzoic acid in 50 ml of concentrated HCl. The solution is stirred for 2 hours at -3° C. and cooled to -10° C., and a solution of 23 g of SnCl2 ·2H2O in 20 ml of concentrated HCl and 20 ml of water is added over 30 minutes. The mixture is stirred for one and a half hours at 0° C. and filtered, and the precipitate is dried to obtain 4 g of expected product.
後処理
- temperaturecooled to -10° C.
- stirringThe mixture is stirred for one and a half hours at 0° C.
- filtrationfiltered
- customthe precipitate is dried
出典と根拠
- ORDレコード
- ord-b9463e90fa6b413699ae9fcde2e663de
- 出典データセット
- uspto-grants-1998_03
- 特許番号
- US05723483
反応ノート
読み込み中…