Diethylamine → HCID 178455924、化合物

HRID 1086126ノート

反応式

HRID 1086126 の反応式
C(NCC)C.[NH:6](C(OCC1C2C(=CC=CC=2)C2C1=CC=CC=2)=O)[C@H:7]([C:11]([NH:13][C@H:14]([C:22]([NH:24][C@H:25]([C:30]([O:32][CH2:33][C:34]1[CH:39]=[CH:38][CH:37]=[CH:36][CH:35]=1)=[O:31])[C@H:26]([CH2:28][CH3:29])[CH3:27])=[O:23])[CH2:15][CH2:16][CH2:17][NH:18][C:19](=[NH:21])[NH2:20])=[O:12])[CH:8]([CH3:10])[CH3:9]>CN(C)C=O>[NH2:6][C@H:7]([C:11]([NH:13][C@H:14]([C:22]([NH:24][C@H:25]([C:30]([O:32][CH2:33][C:34]1[CH:35]=[CH:36][CH:37]=[CH:38][CH:39]=1)=[O:31])[C@H:26]([CH2:28][CH3:29])[CH3:27])=[O:23])[CH2:15][CH2:16][CH2:17][NH:18][C:19](=[NH:20])[NH2:21])=[O:12])[CH:8]([CH3:10])[CH3:9]

参加物

4

反応物 2

HCID 8021DiethylamineHCID 178455925HCID 178455925、化合物

生成物 1

HCID 178455924HCID 178455924、化合物

試薬・触媒・溶媒 1

HCID 6228Dimethylformamide溶媒

実験手順

31.5 ml of diethylamine are added to a solution of 21 g (30 mmol) of Fmoc-Val-Arg-Ile-OBzl in 200 ml of dimethylformamide. The mixture is left to stand at room temperature for 10 minutes, and is concentrated in vacuo. The residue is triturated with diethyl ether and filtered off with suction.

後処理

  1. waitThe mixture is left
  2. concentrationis concentrated in vacuo
  3. customThe residue is triturated with diethyl ether
  4. filtrationfiltered off with suction

出典と根拠

ORDレコード
ord-13a7e8668c1f49ed8ccba1ad01d60636
出典データセット
uspto-grants-1991_04
特許番号
US05011825

反応ノート

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