Genite → Arachidonic Acid

HRID 1086417ノート

反応式

HRID 1086417 の反応式
[C:1]([O-:22])(=[O:21])[CH2:2][CH2:3][CH2:4]/[CH:5]=[CH:6]\[CH2:7]/[CH:8]=[CH:9]\[CH2:10]/[CH:11]=[CH:12]\[CH2:13]/[CH:14]=[CH:15]\[CH2:16][CH2:17][CH2:18][CH2:19][CH3:20].[Na+].C1C=CC(S(OC2C=CC(Cl)=CC=2Cl)(=O)=O)=CC=1.CC1CCCC(C)(C)C=1/C=C/C(/C)=C/C=C/C(/C)=C/C=O.CN1[C@H]2[C@@H](O)C[C@@H]1C[C@H](OC([C@@H](C1C=CC=CC=1)CO)=O)C2>>[C:1]([OH:22])(=[O:21])[CH2:2][CH2:3][CH2:4]/[CH:5]=[CH:6]\[CH2:7]/[CH:8]=[CH:9]\[CH2:10]/[CH:11]=[CH:12]\[CH2:13]/[CH:14]=[CH:15]\[CH2:16][CH2:17][CH2:18][CH2:19][CH3:20]

参加物

5

反応物 4

HCID 7327Genite2 回HCID 638015RetinalHCID 6918612Anisodamine2 回HCID 236754535,8,11,14-Eicosatetraenoic acid, sodium salt, (all-Z)-3 回

生成物 1

HCID 444899Arachidonic Acid

実験手順

Finally, we investigated arachidonic acid-induced lipid peroxidation of the retinal suspension and any protection provided by the presence of anisodamine. Sodium arachidonate was freshly prepared with DPBS by ultrasonification. The experimental system consisted of 0.24 ml of the retinal suspension and, 0.03 ml anisodamine or DPBS for the control. To each tube, excluding the control, 0.03 ml of sodium arachidonate was added. The final concentration of sodium arachidonate was 0.25 mg/ml. The final concentration of anisodamine was 0.01 mg/ml. The malondialdehyde concentration was measured after incubation of the tubes at 37° C. for 30 minutes using the technique discussed previously.

後処理

  1. customTo each tube, excluding
  2. concentrationThe malondialdehyde concentration
  3. customat 37° C.
  4. customfor 30 minutes

出典と根拠

ORDレコード
ord-2677d0db2115458fb54a677295188ea9
出典データセット
uspto-grants-1991_07
特許番号
US05030637

反応ノート

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