Ethyl Dodecanoate → 1-(2-Hydroxyethyl)-2-undecylimidazoline
反応式
[NH2:1][CH2:2][CH2:3][NH:4][CH2:5][CH2:6][OH:7].[C:8](OCC)(=O)[CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][CH3:19]>>[OH:7][CH2:6][CH2:5][N:4]1[CH2:3][CH2:2][N:1]=[C:19]1[CH2:18][CH2:17][CH2:16][CH2:15][CH2:14][CH2:13][CH2:12][CH2:11][CH2:10][CH2:9][CH3:8]参加物
3
実験手順
58.7 g (564.4 mmoles) of 2-(2-aminoethylamino)ethanol and 122.8 g (538.6 mmoles) of ethyl dodecanoate were heated at 125° C. and ethanol was removed by distillation. 100 ml of toluene was cautiously added and water was removed azeotropically on further reflux. The reaction mixture was fractionally distilled to give 100.2 g (69.5%) of pure product, m.p. 40°-42° C.
後処理
- customethanol was removed by distillation
- addition100 ml of toluene was cautiously added
- customwater was removed azeotropically on further reflux
- distillationThe reaction mixture was fractionally distilled
出典と根拠
- ORDレコード
- ord-9a32d83b4e084061b5532e0c93cbc024
- 出典データセット
- uspto-grants-1991_07
- 特許番号
- US05030629
反応ノート
読み込み中…