Ethyl Dodecanoate → 1-(2-Hydroxyethyl)-2-undecylimidazoline

HRID 1086434

反応式

HRID 1086434 の反応式
[NH2:1][CH2:2][CH2:3][NH:4][CH2:5][CH2:6][OH:7].[C:8](OCC)(=O)[CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][CH3:19]>>[OH:7][CH2:6][CH2:5][N:4]1[CH2:3][CH2:2][N:1]=[C:19]1[CH2:18][CH2:17][CH2:16][CH2:15][CH2:14][CH2:13][CH2:12][CH2:11][CH2:10][CH2:9][CH3:8]

参加物

3

反応物 2

HCID 7800Ethyl DodecanoateHCID 8112N-(2-Hydroxyethyl)ethylenediamine

生成物 1

HCID 87091-(2-Hydroxyethyl)-2-undecylimidazoline収率 69.5%

実験手順

58.7 g (564.4 mmoles) of 2-(2-aminoethylamino)ethanol and 122.8 g (538.6 mmoles) of ethyl dodecanoate were heated at 125° C. and ethanol was removed by distillation. 100 ml of toluene was cautiously added and water was removed azeotropically on further reflux. The reaction mixture was fractionally distilled to give 100.2 g (69.5%) of pure product, m.p. 40°-42° C.

後処理

  1. customethanol was removed by distillation
  2. addition100 ml of toluene was cautiously added
  3. customwater was removed azeotropically on further reflux
  4. distillationThe reaction mixture was fractionally distilled

出典と根拠

ORDレコード
ord-9a32d83b4e084061b5532e0c93cbc024
出典データセット
uspto-grants-1991_07
特許番号
US05030629

関連ノート

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