Dimethylamine → Ethyl 3-(N,N-dimethylamino)acrylate
反応式
[CH3:1][NH:2][CH3:3].[CH:4]([CH2:6][C:7]([O:9][CH2:10][CH3:11])=[O:8])=O.[Na]>C1(C)C=CC=CC=1>[CH3:1][N:2]([CH3:3])[CH:4]=[CH:6][C:7]([O:9][CH2:10][CH3:11])=[O:8]参加物
4
反応条件
- 温度
- 20 °C
実験手順
13.1 g (0.29 mol) of dimethylamine were introduced into a suspension of 40 g (0.29 mol) of sodium ethyl formylacetate in 50 ml of toluene and 50 ml of ethanol. HCl gas was then introduced until the point of neutrality was reached and the mixture was stirred at 20° C. for 2 h. After filtering off the precipitate with suction, the mixture was worked up in a customary manner. Ethyl β-dimethylaminoacrylate was obtained in a yield of 91.6%.
後処理
- additionwas then introduced until the point of neutrality
- filtrationAfter filtering off the precipitate with suction
出典と根拠
- ORDレコード
- ord-9078f70fac4248ec96ff214ca2fa8560
- 出典データセット
- uspto-grants-1991_07
- 特許番号
- US05030747
反応ノート
読み込み中…