16-Methylheptadecanoic Acid → Isostearic Acid E-Caprolactone THAM
反応式
[C:1]([OH:20])(=[O:19])[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH:16]([CH3:18])[CH3:17].[CH2:21]1[CH2:28][CH2:27][O:26][C:24](=[O:25])[CH2:23][CH2:22]1.[CH2:29]([OH:36])[C:30]([NH2:35])([CH2:33][OH:34])[CH2:31][OH:32]>>[C:1]([OH:20])(=[O:19])[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH:16]([CH3:17])[CH3:18].[CH2:21]1[CH2:28][CH2:27][O:26][C:24](=[O:25])[CH2:23][CH2:22]1.[CH2:29]([OH:36])[C:30]([NH2:35])([CH2:33][OH:34])[CH2:31][OH:32]参加物
3
反応条件
- 温度
- 180 °C
実験手順
About 28.1 g (0.1 mole) of isostearic acid and 23.5 g (0.1 mol) of the CL-THAM adduct of Example 4 were added to a reaction flask and heated to 180° C. to distill off the water of reaction. The reaction mixture was heated at 180° C. for four hours with mild nitrogen sparging. An infrared analysis of the product showed the desired ester oxazoline. The residue was diluted in solvent 150 neutral mineral oil to make a 50% active ingredient solution and was collected.
後処理
- distillationto distill off
- customthe water of reaction