Hydrochloric Acid → HCID 19818306、化合物

HRID 1086791

反応式

HRID 1086791 の反応式
[CH2:1]([C:16]1[CH:17]=[C:18]([OH:22])[CH:19]=[CH:20][CH:21]=1)[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH3:15].[CH2:23]=[O:24].Cl>O.CO>[OH:24][CH2:23][C:19]1[CH:20]=[CH:21][C:16]([CH2:1][CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH3:15])=[CH:17][C:18]=1[OH:22]

参加物

6

反応物 3

HCID 313Hydrochloric AcidHCID 712FormaldehydeHCID 68146Hydrogenated cardanol

生成物 1

HCID 19818306HCID 19818306、化合物収率 19.4%

試薬・触媒・溶媒 2

HCID 887Methanol溶媒HCID 962Water溶媒

実験手順

(2 1) 150 g of 3-pentadecylphenol and 17.7 g of paraformaldehyde were dispersed in 300 ml of water and 150 ml of methanol, and the dispersion was stirred at 50° C. for 12 hours. The reaction mixture was neutralized with concentrated hydrochloric acid and extracted with ethyl acetate. The extract was dried over anhydrous sodium sulfate and concentrated under reduced pressure. 300 ml of hexane were added to the residue to precipitate a crystal. The crystal was recovered by filtration and dried to obtain 32 g of 2-hydroxymethyl-5-pentadecylphenol.

後処理

  1. extractionextracted with ethyl acetate
  2. dry with materialThe extract was dried over anhydrous sodium sulfate
  3. concentrationconcentrated under reduced pressure
  4. addition300 ml of hexane were added to the residue
  5. customto precipitate a crystal
  6. filtrationThe crystal was recovered by filtration
  7. customdried

出典と根拠

ORDレコード
ord-6acf56d393dc4464b7c0e2eedfc3d797
出典データセット
uspto-grants-1991_07
特許番号
US05032487

関連ノート

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