(2R,3S,4S,5R)-2,3,4,5,6-pentahydroxyhexanal → Lactulose

HRID 1086962

反応式

HRID 1086962 の反応式
[CH2:1]([OH:23])[C@H:2]1[O:7][C@@H:6]([O:8][C@H:9]2[C@H:13]([OH:14])[C@@:12]([OH:17])([CH2:15][OH:16])[O:11][C@@H:10]2[CH2:18][OH:19])[C@H:5]([OH:20])[C@@H:4]([OH:21])[C@H:3]1[OH:22].O.O=C[C@@H]([C@H]([C@H]([C@@H](CO)O)O)O)O>>[CH2:1]([OH:23])[C@H:2]1[O:7][C@@H:6]([O:8][C@H:9]2[C@H:13]([OH:14])[C@@:12]([OH:17])([CH2:15][OH:16])[O:11][C@@H:10]2[CH2:18][OH:19])[C@H:5]([OH:20])[C@@H:4]([OH:21])[C@H:3]1[OH:22]

参加物

3

反応物 2

HCID 3037556(2R,3S,4S,5R)-2,3,4,5,6-pentahydroxyhexanalHCID 66964417(2S,3R,4S,5R,6R)-2-[(2R,3S,4S,5R)-4,5-dihydroxy-2,5-bis(hydroxymethyl)oxolan-3-yl]oxy-6-(hydroxymethyl)oxane-3,4,5-triol;hydrate2 回

生成物 1

HCID 11333Lactulose収率 50.4%

実験手順

A lactulose syrup was prepared in a manner similar to Example 1 except that the chromatography was practiced using XT-1007 (product of Tokyo Organic Chemical Industry Co., Ltd.) (crosslinking degree: 0.6%) as an ion-exchange resin. The peak of lactulose-containing fractions occurred about 123 minutes after the initiation of charging, while the peak of fractions containing monosaccharides such as galactose appeared about 167 minutes after the initiation of charging. The lactulose-containing fractions were collected and concentrated into a syrup, which had the following saccharide composition: 94.3 wt. % of lactulose and 4.2 wt. % of lactose, both based on the whole solids. The solid weight of lactulose was 201.5 kg, and its yield was 50.4% based on the starting lactose.

後処理

  1. waitappeared about 167 minutes
  2. customwere collected
  3. concentrationconcentrated into a syrup, which

出典と根拠

ORDレコード
ord-d4d41a74b2f84f018596b0b82a748131
出典データセット
uspto-grants-1991_07
特許番号
US05034064

関連ノート

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