Potassium Carbonate → 1-(n-Octylsulfonylamino)-8-aminoanthraquinone

HRID 1087304

反応式

HRID 1087304 の反応式
[NH2:1][C:2]1[C:15]2[C:14](=[O:16])[C:13]3[C:8](=[CH:9][CH:10]=[CH:11][C:12]=3Cl)[C:7](=[O:18])[C:6]=2[CH:5]=[CH:4][CH:3]=1.[CH3:19][CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][CH2:25][CH2:26][S:27]([NH2:30])(=[O:29])=[O:28].C(=O)([O-])[O-].[K+].[K+]>ClC1C=CC=CC=1>[CH2:26]([S:27]([NH:30][C:12]1[C:13]2[C:14](=[O:16])[C:15]3[C:6](=[CH:5][CH:4]=[CH:3][C:2]=3[NH2:1])[C:7](=[O:18])[C:8]=2[CH:9]=[CH:10][CH:11]=1)(=[O:29])=[O:28])[CH2:25][CH2:24][CH2:23][CH2:22][CH2:21][CH2:20][CH3:19]

参加物

5

反応物 3

HCID 11430Potassium CarbonateHCID 2236691-Amino-8-chloroanthraquinoneHCID 2295971-Octanesulfonamide

生成物 1

HCID 198180061-(n-Octylsulfonylamino)-8-aminoanthraquinone

試薬・触媒・溶媒 1

HCID 7964Chlorobenzene溶媒

実験手順

1-(n-octylsulfonylamino)-8-aminoanthraquinone was prepared as follows. 1-amino-8-chloroanthraquinone (1.0g), n-octanesulfonamide (1.0g), potassium carbonate (1.0g), cupric acetate monohydrate (0.85g) and chlorobenzene (16.0g) were refluxed for 5.5 hours. The cooled mixture was filtered and aqueous methanol was added to the filtrate. The supernatant liquid was decanted and the remaining oil was dissolved in dichloromethane. On addition of methanol and partial evaporation of the solvent, the product separated as a red solid.

後処理

  1. filtrationThe cooled mixture was filtered
  2. additionaqueous methanol was added to the filtrate
  3. customThe supernatant liquid was decanted
  4. dissolutionthe remaining oil was dissolved in dichloromethane
  5. additionOn addition of methanol and partial evaporation of the solvent
  6. customthe product separated as a red solid

出典と根拠

ORDレコード
ord-83651583e42e4f30a2ee99efb5716dee
出典データセット
uspto-grants-1991_07
特許番号
US05034547

関連ノート

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