Epichlorohydrin → 3-(2-Benzyl-4-chlorophenoxy)-1,2-epoxypropane

HRID 1087405

反応式

HRID 1087405 の反応式
[CH2:1]([C:8]1[CH:13]=[C:12]([Cl:14])[CH:11]=[CH:10][C:9]=1[OH:15])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.Cl[CH2:17][CH:18]1[O:20][CH2:19]1.C(=O)([O-])[O-].[K+].[K+]>CC(=O)CC>[CH2:1]([C:8]1[CH:13]=[C:12]([Cl:14])[CH:11]=[CH:10][C:9]=1[O:15][CH2:17][CH:18]1[O:20][CH2:19]1)[C:2]1[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=1

参加物

5

反応物 3

HCID 7835EpichlorohydrinHCID 8425ChloropheneHCID 11430Potassium Carbonate

生成物 1

HCID 143699403-(2-Benzyl-4-chlorophenoxy)-1,2-epoxypropane

試薬・触媒・溶媒 1

HCID 6569Methyl Ethyl Ketone溶媒

実験手順

A suspension containing 21.87 g of 2-benzyl-4-chlorophenol, 27.76 g of 1-chloro-2,3-epoxypropane and 27.64 g of potassium carbonate in 200 ml of butanone is refluxed for 12 hours. The inorganic salts formed are filtered off and drained. The solvent and excess 1-chloro-2,3-epoxypropane are evaporated off under vacuum and the residue is distilled at between 160° C. and 180° C. under 0.01 mm of mercury.

後処理

  1. temperatureis refluxed for 12 hours
  2. customThe inorganic salts formed
  3. filtrationare filtered off
  4. customThe solvent and excess 1-chloro-2,3-epoxypropane are evaporated off under vacuum
  5. distillationthe residue is distilled at between 160° C. and 180° C. under 0.01 mm of mercury

出典と根拠

ORDレコード
ord-f9f619d136424341bc05c2fa1bf5aa73
出典データセット
uspto-grants-1991_07
特許番号
US05036077

関連ノート

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