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Diethyl Ether → N-(4-Benzyloxybenzyl)-N-(t-butylcarbonyloxy)acetamide
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Diethyl Ether | HCID 3283 | — |
| 反応物 | Triethylamine | HCID 8471 | — |
| 反応物 | Pivaloyl chloride | HCID 62493 | — |
| 反応物 | N-(4-benzyloxybenzyl)acetohydroxamic acid | HCID 129265 | — |
| 溶媒 | Dichloromethane | HCID 6344 | — |
| 溶媒 | 2-Dimethylaminopyridine | HCID 21885 | — |
| 生成物 | N-(4-Benzyloxybenzyl)-N-(t-butylcarbonyloxy)acetamide | HCID 19817263 | — |
反応手順
Pivaloylchloride (1.36 ml) was added dropwise to a solution of N-(4-benzyloxybenzyl)acetohydroxamic acid (2.71 g) and triethylamine (1.7 ml) in methylene dichloride (15 ml) and dimethylaminopyridine (100 ml). The mixture was stirred for 2 hours at room temperature, then neutral material was isolated with ether. The product, N-(4-(Benzyloxybenzyl)-N-(t-butylcarbonyloxy)acetamide, was a colourless oil.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US05036157 |
| 出典データセット | uspto-grants-1991_07 |
| ORD ID | ord-dc3e59f89ed741099e8fc04c481bc66a |
| 出典メモ | uspto-grants-1991_07 |