N,N,N',N'-Tetramethylmethanediamine → HCID 14556367、化合物
反応式
[CH3:1][N:2]1[C:6]2[CH:7]=[CH:8][C:9]([C:11](=[O:14])[CH2:12][CH3:13])=[CH:10][C:5]=2[O:4][C:3]1=[O:15].[CH3:16]N(CN(C)C)C.C(OC(=O)C)(=O)C>>[CH3:1][N:2]1[C:6]2[CH:7]=[CH:8][C:9]([C:11](=[O:14])[C:12](=[CH2:16])[CH3:13])=[CH:10][C:5]=2[O:4][C:3]1=[O:15]参加物
4
反応条件
- 温度
- 100 °C
実験手順
0.01 mole of 3-methyl-6-propionylbenzoxazolinone and 0.04 mole of bis(dimethylamino)methane are introduced into a 150-cm3 ground-necked flask equipped with a reflux condenser and a magnetic stirrer. 15 cm3 of acetic anhydride are added dropwise and the mixture is heated to 100° C. for 5 hours. After being cooled, the reaction mixture is poured into 5 volumes of ice-cold water. The mixture is acidified and stirred for one hour, and the product is drained, washed with water to neutrality, dried and recrystallized in hexane.