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Hydrazine hydrate (1:1) → 1-Hydrazino-2-methyl-4-nitrobenzene hydrofluoride
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Hydrazine hydrate (1:1) | HCID 24654 | — |
| 反応物 | Benzene, 1-fluoro-2-methyl-4-nitro- | HCID 68001 | — |
| 溶媒 | Isopropanol | HCID 3776 | — |
| 生成物 | 1-Hydrazino-2-methyl-4-nitrobenzene hydrofluoride | HCID 22111787 | — |
反応手順
A mixture of 4.6 g of 1-fluoro-2-methyl-4-nitrobenzene and 3 ml of hydrazine hydrate in 45 ml of 2-propanol is heated to reflux for 2 hours. 3 ml of hydrazine hydrate are added, refluxing is continued for 2 hours and the mixture is left overnight with stirring at RT. The precipitate formed is drained. 3.53 g of the expected product are obtained, m.p.=182° C.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US05723483 |
| 出典データセット | uspto-grants-1998_03 |
| ORD ID | ord-58c913b2ad0b45c7913c1bbe8dd60541 |
| 出典メモ | uspto-grants-1998_03 |