Sodium Chloride → 2-Amino-6-methoxyphenol
反応式
[CH3:1][O:2][C:3]1[CH:8]=[CH:7][CH:6]=[C:5]([N+:9]([O-])=O)[C:4]=1[OH:12].S(S([O-])=O)([O-])=O.[Na+].[Na+].[Cl-].[Na+]>O.CO>[NH2:9][C:5]1[CH:6]=[CH:7][CH:8]=[C:3]([O:2][CH3:1])[C:4]=1[OH:12]参加物
6
反応条件
- 温度
- 60 °C
実験手順
To a suspension of 4.72 g of 2-methoxy 6-nitrophenol in a mixture of 100 ml of water and 30 ml of methanol was added 29.3 g of sodium dithionite. The mixture was stirred at 60° C. until it became a uniform and colorless solution. To the reaction mixture was added a saturated aqueous solution of sodium chloride. The mixture was extracted with ethyl acetate and dried over anhydrous sodium sulfate. After the drying agent was filtered off, the solvent was distilled off under reduced pressure to give 3.65 g of crude 2-amino-6-methoxyphenol.
後処理
- extractionThe mixture was extracted with ethyl acetate
- dry with materialdried over anhydrous sodium sulfate
- filtrationAfter the drying agent was filtered off
- distillationthe solvent was distilled off under reduced pressure
出典と根拠
- ORDレコード
- ord-c630a99d6e8146909aed3ba1e297fec9
- 出典データセット
- uspto-grants-1990_10
- 特許番号
- US04965261
反応ノート
読み込み中…