Ammonia → HCID 13876411、化合物

HRID 1089132

反応式

HRID 1089132 の反応式
[CH3:1][O:2][C:3]1[CH:13]=[C:12]([C:14]#[N:15])[CH:11]=[CH:10][C:4]=1[O:5][CH2:6][C:7]([OH:9])=[O:8].N>[Ni].CO>[CH3:1][O:2][C:3]1[CH:13]=[C:12]([CH2:14][NH2:15])[CH:11]=[CH:10][C:4]=1[O:5][CH2:6][C:7]([OH:9])=[O:8]

参加物

5

反応物 2

HCID 222AmmoniaHCID 12209582-(4-Cyano-2-methoxyphenoxy)acetic acid

生成物 1

HCID 13876411HCID 13876411、化合物

試薬・触媒・溶媒 2

HCID 935Nickel触媒HCID 887Methanol溶媒

実験手順

3.3 g of 2-(2-methoxy-4-cyanophenoxy)-acetic acid are hydrogenated in 90 ml of a 2:1 (by volume) mixture of methanol and 25% aqueous ammonia in the presence of 1.6 g of Raney nickel for 5 hours at room temperature under normal pressure. After filtering off the catalyst, it is washed with methanol and water and the filtrate is then concentrated to dryness. The resulting solid material is triturated with a small amount of water, filtered off and dried over P2O5 in an exsiccator.

後処理

  1. filtrationAfter filtering off the catalyst, it
  2. washis washed with methanol and water
  3. concentrationthe filtrate is then concentrated to dryness
  4. customThe resulting solid material is triturated with a small amount of water
  5. filtrationfiltered off
  6. dry with materialdried over P2O5 in an exsiccator

出典と根拠

ORDレコード
ord-5c964da8f7d04622a287b1ab22922095
出典データセット
uspto-grants-1990_10
特許番号
US04965260

関連ノート

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