Diethyl isobutylmalonate → 2-Isobutyl-2-hydroxymethylpropan-1,3-diol

HRID 1089141ノート

反応式

HRID 1089141 の反応式
[CH:1]1([CH:7]([C:13]([O:15]CC)=O)[C:8]([O:10]CC)=O)[CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]1.C(C(C(OCC)=O)[C:23](OCC)=[O:24])C(C)C.[CH3:33][C:34](C)([CH3:43])[CH2:35][C:36]([CH2:41][OH:42])([CH2:39][OH:40])[CH2:37][OH:38]>>[CH:1]1([C:7]([CH2:8][OH:10])([CH2:13][OH:15])[CH2:23][OH:24])[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6]1.[CH2:35]([C:36]([CH2:37][OH:38])([CH2:39][OH:40])[CH2:41][OH:42])[CH:34]([CH3:43])[CH3:33]

参加物

5

反応物 3

HCID 25047Diethyl isobutylmalonateHCID 240541Diethyl 2-cyclohexylmalonateHCID 18953343HCID 18953343、化合物

生成物 2

HCID 129305352-Isobutyl-2-hydroxymethylpropan-1,3-diolHCID 129305402-Cyclohexyl-2-hydroxymethylpropan-1,3-diol

実験手順

2-Cyclohexyl-2-hydroxymethylpropan-1,3-diol and 2-isobutyl-2-hydroxymethylpropan-1,3-diol were prepared from diethyl cyclohexylmalonate and diethyl i-butylmalonate respectively in a manner analogous to the synthesis of 2-(2,2-dimethylpropyl)-2-hydroxymethylpropane-1,3-diol (example 5).

出典と根拠

ORDレコード
ord-91f1a09187a44b739e2b22be84ba9f01
出典データセット
uspto-grants-1990_10
特許番号
US04965257

反応ノート

読み込み中…