Phosphorus oxychloride → HCID 178432280、化合物

HRID 1089758

反応式

HRID 1089758 の反応式
[C:1]([C:4]1[N:5]=[CH:6][N:7]2[C:12]([OH:13])=[C:11]([CH2:14][CH2:15]O)[C:10]([CH3:17])=[N:9][C:8]=12)(=O)[NH2:2].P(Cl)(Cl)([Cl:20])=O>>[Cl:20][CH2:15][CH2:14][C:11]1[C:10]([CH3:17])=[N:9][C:8]2[N:7]([CH:6]=[N:5][C:4]=2[C:1]#[N:2])[C:12]=1[OH:13]

参加物

3

反応物 2

HCID 24813Phosphorus oxychlorideHCID 178432286HCID 178432286、化合物

生成物 1

HCID 178432280HCID 178432280、化合物

実験手順

0.17 mol of the compound obtained in Stage A of Example 3, dissolved in 200 ml of phosphorus oxychloride, is brought to 85° C. for one hour 30 minutes. The phosphorus oxychloride is then removed by evaporation under vacuum. 100 ml of water are added and the pH is adjusted to 7 using sodium bicarbonate to crystallize the expected compound. The latter is filtered off.

後処理

  1. customThe phosphorus oxychloride is then removed by evaporation under vacuum
  2. addition100 ml of water are added
  3. customto crystallize the expected compound
  4. filtrationThe latter is filtered off

出典と根拠

ORDレコード
ord-a1bff64a3f104ec58719b96b88408190
出典データセット
uspto-grants-1992_01
特許番号
US05079249

関連ノート

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