化工社化工社 化学情報印刷レポート · 研究参考用
2-Methyl-3-nitrobenzyl alcohol → (3-Amino-2-methylphenyl)methanol
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 2-Methyl-3-nitrobenzyl alcohol | HCID 90289 | — |
| 触媒 | Palladium | HCID 23938 | — |
| 溶媒 | Ethanol | HCID 702 | — |
| 生成物 | (3-Amino-2-methylphenyl)methanol | HCID 577175 | 101.4% |
反応手順
A solution of 2-methyl-3-nitrobenzyl alcohol (2.0 g, 12 mmol) in ethanol (100 ml) was hydrogenated over 10% palladium/charcoal (0.1 g) for 2 hours, at an initial pressure of 3.5 bar. The solution was filtered through celite and evaporated to give 3-amino-2-methylbenzyl alcohol (1.67 g, quantitative), m.p. 104°-106°
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US05082848 |
| 出典データセット | uspto-grants-1992_01 |
| ORD ID | ord-964ca6295eb64af1ac47407e4136b9c0 |
| 出典メモ | uspto-grants-1992_01 |