Water → 4-Morpholino-2-nitrobenzonitrile

HRID 1091531

反応式

HRID 1091531 の反応式
[N+:1]([C:4]1[CH:11]=[C:10]([N+:12]([O-])=O)[CH:9]=[CH:8][C:5]=1[C:6]#[N:7])([O-:3])=[O:2].N1[CH2:20][CH2:19][O:18][CH2:17][CH2:16]1.O>CN(C)C=O>[N:12]1([C:10]2[CH:9]=[CH:8][C:5]([C:6]#[N:7])=[C:4]([N+:1]([O-:3])=[O:2])[CH:11]=2)[CH2:20][CH2:19][O:18][CH2:17][CH2:16]1

参加物

5

反応物 3

HCID 962WaterHCID 8083MorpholineHCID 5540822,4-Dinitrobenzonitrile

生成物 1

HCID 134992654-Morpholino-2-nitrobenzonitrile収率 82.8%

試薬・触媒・溶媒 1

HCID 6228Dimethylformamide溶媒

実験手順

A mixture of 2,4-dinitrobenzonitrile 4.20 g (21.75 mmol) and morpholine 5.7 mL (66.0 mmol) in N,N-dimethylformamide 20 mL was stirred at room temperature for 20 hours. The reaction mixture was poured into water. The precipitate was collected and washed with water to give the title compound 4.20 g as orange solid. Yield 74.5%.

後処理

  1. customThe precipitate was collected
  2. washwashed with water

出典と根拠

ORDレコード
ord-02cebe0ec2ed4d2abe6ec47f4a5a4591
出典データセット
uspto-grants-2012_03
特許番号
US08129386B2

関連ノート

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