Methanesulfonyl chloride → 3-{[3-(2-Chloro-pyrimidin-4-yl)-benzyl]-methanesulfonyl-amino}-pyrrolidine-1-carboxylic acid tert-butyl ester

HRID 109250

反応式

[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH:10]([NH:13][CH2:14][c:15]2[cH:16][c:17](-[c:21]3[n:22][c:23]([Cl:27])[n:24][cH:25][cH:26]3)[cH:18][cH:19][cH:20]2)[CH2:11][CH2:12]1.[CH3:28][S:29]([Cl:30])(=[O:31])=[O:32]>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH:10]([N:13]([CH2:14][c:15]2[cH:16][c:17](-[c:21]3[n:22][c:23]([Cl:27])[n:24][cH:25][cH:26]3)[cH:18][cH:19][cH:20]2)[S:29]([CH3:28])(=[O:31])=[O:32])[CH2:11][CH2:12]1