Bromine → 1-Bromo-1-(3-methanesulphonyl-phenyl)-propanone

HRID 1093015ノート

反応式

HRID 1093015 の反応式
[CH3:1][S:2]([C:5]1[CH:6]=[C:7]([CH2:11][C:12](=[O:14])[CH3:13])[CH:8]=[CH:9][CH:10]=1)(=[O:4])=[O:3].[Br:15]Br>O1CCOCC1>[Br:15][CH:11]([C:7]1[CH:8]=[CH:9][CH:10]=[C:5]([S:2]([CH3:1])(=[O:3])=[O:4])[CH:6]=1)[C:12](=[O:14])[CH3:13]

参加物

4

反応物 2

HCID 24408BromineHCID 665884811-(3-(Methylsulfonyl)phenyl)propan-2-one

生成物 1

HCID 858616531-Bromo-1-(3-methanesulphonyl-phenyl)-propanone

試薬・触媒・溶媒 1

HCID 312751,4-Dioxane溶媒

実験手順

A stirred solution of 1-(3-methanesulphonyl-phenyl)-propan-2-one (176b) (0.25 g, 1.18 mmol) in dioxane (10 ml) at 5° C. is treated with bromine (0.131 g, 0.82 mmol) added in two portions. The reaction is stirred and allowed to warm up to room temperature. The solvent is removed in vacuo to yield an orange oil of the titled compound.

後処理

  1. additionadded in two portions
  2. customThe solvent is removed in vacuo

出典と根拠

ORDレコード
ord-7322d988ca48436db43a24f062528d8b
出典データセット
uspto-grants-2012_03
特許番号
US08129541B2

反応ノート

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