2-(5-Trifluoromethyl-pyridin-2-YL)-ethylamine → HCID 58007506、化合物
反応式
I[C:2]1[CH:7]=[CH:6][C:5]([CH3:8])=[C:4]([O:9][CH:10]([F:12])[F:11])[CH:3]=1.[F:13][C:14]([F:25])([F:24])[C:15]1[CH:16]=[CH:17][C:18]([CH2:21][CH2:22][NH2:23])=[N:19][CH:20]=1>>[F:11][CH:10]([F:12])[O:9][C:4]1[CH:3]=[C:2]([NH:23][CH2:22][CH2:21][C:18]2[CH:17]=[CH:16][C:15]([C:14]([F:25])([F:13])[F:24])=[CH:20][N:19]=2)[CH:7]=[CH:6][C:5]=1[CH3:8]参加物
3
実験手順
In analogy to the procedure described for the synthesis example 71 (step 1), the title compound (3-difluoromethoxy-4-methyl-phenyl)-[2-(5-trifluoromethyl-pyridin-2-yl)-ethyl]-amine (MS m/e: 347.1 [M+H]+) was prepared from 4-iodo-2-difluoromethoxy-toluene instead of 6-bromo-2,3-dihydro-benzofuran and 2-(5-trifluoromethyl-pyridin-2-yl)-ethylamine instead of 2-(6-trifluoromethyl-pyridin-3-yl)-ethylamine.
後処理
- customIn analogy to the procedure described for the synthesis example 71 (step 1)
出典と根拠
- ORDレコード
- ord-d2536e1ae38142e1bc030e04fd210d1c
- 出典データセット