5-Amino-5-ethyl-1-phenylbarbituric acid → N-(5-Ethyl-hexahydro-2,4,6-trioxo-1-phenyl-5-pyrimidinyl)-2,3,4,5-tetrafluorobenzamide

HRID 1097283ノート

反応式

HRID 1097283 の反応式
C(N1C(=O)C(N[C:12](=[O:23])[C:13]2[CH:18]=[C:17]([F:19])[C:16]([F:20])=[C:15]([F:21])[C:14]=2[F:22])(C)C(=O)NC1=O)C.[NH2:26][C:27]1([CH2:42][CH3:43])[C:32](=[O:33])[N:31]([C:34]2[CH:39]=[CH:38][CH:37]=[CH:36][CH:35]=2)[C:30](=[O:40])[NH:29][C:28]1=[O:41]>>[CH2:42]([C:27]1([NH:26][C:12](=[O:23])[C:13]2[CH:18]=[C:17]([F:19])[C:16]([F:20])=[C:15]([F:21])[C:14]=2[F:22])[C:32](=[O:33])[N:31]([C:34]2[CH:39]=[CH:38][CH:37]=[CH:36][CH:35]=2)[C:30](=[O:40])[NH:29][C:28]1=[O:41])[CH3:43]

参加物

3

反応物 2

HCID 154249375-Amino-5-ethyl-1-phenylbarbituric acidHCID 24765666N-(1-Ethyl-hexahydro-5-methyl-2,4,6-trioxo-5-pyrimidinyl)-2,3,4,5-tetrafluorobenzamide

生成物 1

HCID 24765564N-(5-Ethyl-hexahydro-2,4,6-trioxo-1-phenyl-5-pyrimidinyl)-2,3,4,5-tetrafluorobenzamide

実験手順

Compound 20k was prepared by the same method described for 20f using 5-amino-5-ethyl-1-phenylbarbituric acid (0.50 g, 2 mmol). The crude 5-ethyl-1-phenyl-5-(tetrafluorobenz-amido)barbituric acid (20k) was obtained as yellow crystals that were pure.

後処理

  1. customCompound 20k was prepared by the same method

出典と根拠

ORDレコード
ord-31fcb5f2b20d40d192ce55cbffc9c114
出典データセット
uspto-grants-2012_03
特許番号
US08143252B2

反応ノート

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