7-Chloro-5-[[(2,3-difluorophenyl)methyl]thio]-thiazolo[4,5-d]pyrimidin-2-amine → (+/-)-2-[[2-Amino-5-[[(2,3-difluorophenyl)methyl]thio]thiazolo[4,5-d]pyrimidin-7-yl]amino]-3-methoxy-1-propanol
反応式
Cl[C:2]1[C:3]2[S:20][C:19]([NH2:21])=[N:18][C:4]=2[N:5]=[C:6]([S:8][CH2:9][C:10]2[CH:15]=[CH:14][CH:13]=[C:12]([F:16])[C:11]=2[F:17])[N:7]=1.Cl.[NH2:23][CH:24]([CH2:27][O:28][CH3:29])[CH2:25][OH:26]>>[NH2:21][C:19]1[S:20][C:3]2[C:2]([NH:23][CH:24]([CH2:27][O:28][CH3:29])[CH2:25][OH:26])=[N:7][C:6]([S:8][CH2:9][C:10]3[CH:15]=[CH:14][CH:13]=[C:12]([F:16])[C:11]=3[F:17])=[N:5][C:4]=2[N:18]=1参加物
3
実験手順
Prepared by the method of example 12 step a) using the product of example 4 step b) and the product of example 40 step a).
後処理
- customPrepared by the method of example 12 step a)
出典と根拠
- ORDレコード