4-Methoxybenzaldehyde → N-(4-Methoxybenzylidene)-N-(4-methoxybenzyl)amine

反応式

[CH3:1][O:2][C:3]1[CH:10]=[CH:9][C:6]([CH2:7][NH2:8])=[CH:5][CH:4]=1.[CH:11](=O)[C:12]1[CH:17]=[CH:16][C:15]([O:18][CH3:19])=[CH:14][CH:13]=1>>[CH3:1][O:2][C:3]1[CH:10]=[CH:9][C:6]([CH2:7][N:8]=[CH:11][C:12]2[CH:17]=[CH:16][C:15]([O:18][CH3:19])=[CH:14][CH:13]=2)=[CH:5][CH:4]=1

参加物

反応物 2

HCID 312444-Methoxybenzaldehyde

HCID 754524-Methoxybenzylamine

生成物 1

HCID 578709N-(4-Methoxybenzylidene)-N-(4-methoxybenzyl)amine収率 131%

実験手順

4-Methoxybenzylamine (40 g, 290 mmol) was cooled to 0° C., and p-anisaldehyde (39.7 g, 292 mmol) was added dropwise. The reaction was stirred at ambient temperature for two hours, concentrated under reduced pressure, and further dried under high vacuum overnight to provide 97 g of N-(4-methoxybenzyl)-N-[(4-methoxyphenyl)methylidene]amine as a white, waxy solid.

後処理

concentrationconcentrated under reduced pressure
customfurther dried under high vacuum overnight

出典と根拠

ORDレコード: ord-b566f8d0d4604980b48691a32407a87c
出典データセット: uspto-grants-2012_03
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US08143270B2

反応ノート

読み込み中…

参加物