(4-Methoxyphenyl)hydrazine → 5-Bromo-1-(4-methoxy-phenyl)-1H-indazole

反応式

[CH3:1][O:2][C:3]1[CH:8]=[CH:7][C:6]([NH:9][NH2:10])=[CH:5][CH:4]=1.Br[C:12]1[CH:19]=[CH:18][C:17]([Br:20])=[CH:16][C:13]=1[CH:14]=O>>[Br:20][C:17]1[CH:16]=[C:13]2[C:12](=[CH:19][CH:18]=1)[N:9]([C:6]1[CH:7]=[CH:8][C:3]([O:2][CH3:1])=[CH:4][CH:5]=1)[N:10]=[CH:14]2

参加物

反応物 2

HCID 77023(4-Methoxyphenyl)hydrazine

HCID 135400692,5-Dibromobenzaldehyde

生成物 1

HCID 574213515-Bromo-1-(4-methoxy-phenyl)-1H-indazole

実験手順

In analogy to Example 187, step 1, 4-methoxyphenylhydrazine was reacted with 2,5-dibromobenzaldehyde to give the title compound as a light brown solid. MS (m/e)=303.0 [M+H+].

出典と根拠

ORDレコード: ord-95b6baee070b4023b78896d067c510fa
出典データセット: uspto-grants-2012_03
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US08143280B2

反応ノート

読み込み中…