2-(Ethoxymethylene)propanedinitrile → HCID 57438678、化合物
反応式
C(O[CH:4]=[C:5]([C:8]#[N:9])[C:6]#[N:7])C.[Br:10][C:11]1[CH:16]=[CH:15][CH:14]=[C:13]([Br:17])[C:12]=1[NH:18][NH2:19]>CO>[NH2:9][C:8]1[N:18]([C:12]2[C:11]([Br:10])=[CH:16][CH:15]=[CH:14][C:13]=2[Br:17])[N:19]=[CH:4][C:5]=1[C:6]#[N:7]参加物
4
実験手順
2-(Ethoxymethylene)malononitrile (197 mg, 1.62 mmol) was added portionwise to a stirred solution of (2,6-dibromophenyl)hydrazine (CAS no. 14763-29-2) (430 mg, 1.62 mmol) in MeOH (8085 μl), under nitrogen at 5° C. The resulting solution was allowed to stir for a further 1 hour. The reaction mixture was then heated to reflux and was stirred for 3 hours. The reaction mixture was allowed to cool to ambient temperature, then was evaporated to afford crude product which was used without further purification.
後処理
- customat 5° C
- temperatureThe reaction mixture was then heated
- temperatureto reflux
- stirringwas stirred for 3 hours
- customwas evaporated
- customto afford crude product which
- customwas used without further purification
出典と根拠
- ORDレコード
- ord-4ce93026e0af415a9c82a8c63e130346
- 出典データセット
- uspto-grants-2012_03
- 特許番号
- US08143263B2
反応ノート
読み込み中…