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HRID 10984作成日：2026年10月26日

3-benzyloxycarbonylamino-6-methyl-4-oxo-4,6,7,8-tetrahydro-pyrrolo[1,2-a]pyrimidine-6-carboxylic Acid → 3-benzyloxycarbonylamino-6-methoxymethyl-4-oxo-4,6,7,8-tetrahydro-pyrrolo[1,2-a]pyrimidine-6-carboxylic Acid

https://huagongshe.com/reaction/10984

反応式

関与物質

役割名称HCID仕込み量
反応物3-benzyloxycarbonylamino-6-methyl-4-oxo-4,6,7,8-tetrahydro-pyrrolo[1,2-a]pyrimidine-6-carboxylic AcidHCID 21979698—
反応物3-benzyloxycarbonylamino-6-methoxymethyl-4-oxo-4,6,7,8-tetrahydro-pyrrolo[1,2-a]pyrimidine-6-carboxylic Acid tert-butyl EsterHCID 69600581—
生成物3-benzyloxycarbonylamino-6-methoxymethyl-4-oxo-4,6,7,8-tetrahydro-pyrrolo[1,2-a]pyrimidine-6-carboxylic AcidHCID 21979643—

反応手順

According to the procedure for the preparation of intermediate 19b, intermediate 23a (87 mg, 0.203 mmol) was deprotected to afford 76 mg (quantitative) of intermediate 23b. MS (ESI) 418.3 (M 2Na++H+), 372.2 (M−H+).

情報源と証拠

DOI10.6084/m9.figshare.5104873.v1
特許番号US07094783B2
出典データセットuspto-grants-2006_08
ORD IDord-96eaada888e34835aeae2998f8196457
出典メモuspto-grants-2006_08