3-Phenoxy-1,2-propanediol → Phenoxyacetaldehyde

HRID 1098840

反応式

HRID 1098840 の反応式
I([O-])(=O)(=O)=O.[Na+].[O:7]([CH2:14][CH:15]([OH:18])CO)[C:8]1[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=1>ClCCl>[O:7]([CH2:14][CH:15]=[O:18])[C:8]1[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=1

参加物

4

反応物 2

HCID 108573-Phenoxy-1,2-propanediolHCID 23667635Sodium periodate

生成物 1

HCID 75033Phenoxyacetaldehyde収率 100%

試薬・触媒・溶媒 1

HCID 6344Dichloromethane溶媒2 回

実験手順

Sodium periodate (0.65 M in water, 20 mL) was added to a vigorously stirred suspension of silica gel (20 g) in dichloromethane (160 mL), followed by a solution of 3-phenoxy-1,2-propanediol (1.68 g, 10.0 mmol) in dichloromethane (20 mL). After stirring for 10 min the mixture was filtered and the filtrate was concentrated to give the subtitle compound (1.36 g, 100%).

後処理

  1. filtrationwas filtered
  2. concentrationthe filtrate was concentrated

出典と根拠

ORDレコード
ord-15b9268a4a2f477988dae515e9076246
出典データセット
uspto-grants-2012_03
特許番号
US08143290B2

関連ノート

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