[(Aminocarbonyl)hydrazono](phenyl)acetaldehyde → 6-Phenyl-1,2,4-triazin-3(2H)-one

HRID 1099030ノート

反応式

HRID 1099030 の反応式
[NH2:1][C:2]([NH:4][N:5]=[C:6]([C:9]1[CH:14]=[CH:13][CH:12]=[CH:11][CH:10]=1)[CH:7]=O)=[O:3]>C(O)(=O)C>[C:9]1([C:6]2[CH:7]=[N:1][C:2](=[O:3])[NH:4][N:5]=2)[CH:14]=[CH:13][CH:12]=[CH:11][CH:10]=1

参加物

3

反応物 1

HCID 54444391[(Aminocarbonyl)hydrazono](phenyl)acetaldehyde

生成物 1

HCID 112637836-Phenyl-1,2,4-triazin-3(2H)-one収率 90.1%

試薬・触媒・溶媒 1

HCID 176Acetic Acid溶媒

実験手順

[(Aminocarbonyl)hydrazono](phenyl)acetaldehyde (3.00 g, 0.0157 mol) in acetic acid (15.0 mL) was heated at 130° C. for 6 h. After cooling, the solvent was removed under reduced pressure. The residue was triturated with ether, filtered, washed with ether, and dried under high vacuum to give the desired product (2.45 g, 90.1%). Analytical LCMS: (M+H)+=174.0.

後処理

  1. temperatureAfter cooling
  2. customthe solvent was removed under reduced pressure
  3. customThe residue was triturated with ether
  4. filtrationfiltered
  5. washwashed with ether
  6. customdried under high vacuum

出典と根拠

ORDレコード
ord-7df081a83a6040e1878edd9837546375
出典データセット
uspto-grants-2012_03
特許番号
US08143251B2

反応ノート

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