Naphthalene → n-Butyl 2-hydroxy-3-butenoate

反応式

C(O)[C@H]1[O:7][C@H:6]([O:8][C@:9]2(CO)O[C@H:12](CO)[C@@H:11](O)[C@@H:10]2O)[C@H:5]([OH:20])[C@@H:4](O)[C@@H:3]1O.C1C2C(=CC=CC=2)C=CC=1.C(OCCCC)(=O)C(C)O>C(O)CCC>[OH:20][CH:5]([CH:4]=[CH2:3])[C:6]([O:8][CH2:9][CH2:10][CH2:11][CH3:12])=[O:7]

参加物

反応条件

温度: 160 °C

実験手順

An autoclave (50 cc microclave) is charged with 8.0 g of 1-butanol, 0.2249 g of sucrose (0.6569 mmol), 121.0 mg naphthalene (internal standard) and finally with 160.5 mg Sn-BEA (prepared according to U.S. Pat. No. 6,306,364). The autoclave is closed, charged with 20 bar of argon and heated to 160° C. After the temperature reaches 100° C., the mechanical stirrer is started (500 rpm) and the mixture is heated for 20 hours under these conditions. GC-analysis of the reaction mixture shows that 0.68 mmol of n-butyl lactate is formed (26%) together with 0.164 mmol n-butyl 2-hydroxy-3-butenoate (8%).