N-(4-bromophenyl)-8-chloro-2-oxo-2H-chromene-3-sulfonamide → 6-bromo-N-(4-methoxyphenyl)-2-oxo-2H-chromene-3-sulfonamide

HRID 1099701ノート

反応式

HRID 1099701 の反応式
Cl[C:2]1[CH:3]=[C:4]2[C:9](=[CH:10][CH:11]=1)[O:8][C:7](=[O:12])[C:6]([S:13]([NH:16][C:17]1[CH:22]=[CH:21][C:20]([O:23][CH3:24])=[CH:19][CH:18]=1)(=[O:15])=[O:14])=[CH:5]2.C(OC1C=CC=C2C=1OC(=O)C(S(NC1C=CC(OC)=CC=1)(=O)=O)=C2)C.ClC1C=C2C(=CC=1)OC(=O)C(S(NC1C=CC(OC)=C(O)C=1)(=O)=O)=C2.NC1C=C(NS(C2C(=O)OC3C(C=2)=CC=CC=3OCC)(=O)=O)C=CC=1F.NC1C=C(NS(C2C(=O)OC3C(C=2)=CC(OC)=CC=3)(=O)=O)C=CC=1F.[Br:127]C1C=CC(NS(C2C(=O)OC3C(C=2)=CC(OC)=CC=3)(=O)=O)=CC=1.BrC1C=CC(NS(C2C(=O)OC3C(C=2)=CC=CC=3Cl)(=O)=O)=CC=1.BrC1C=CC(NS(C2C(=O)OC3C(C=2)=CC=CC=3Br)(=O)=O)=CC=1>>[Br:127][C:2]1[CH:3]=[C:4]2[C:9](=[CH:10][CH:11]=1)[O:8][C:7](=[O:12])[C:6]([S:13]([NH:16][C:17]1[CH:22]=[CH:21][C:20]([O:23][CH3:24])=[CH:19][CH:18]=1)(=[O:15])=[O:14])=[CH:5]2

参加物

9

反応物 8

HCID 10047436N-(4-bromophenyl)-8-chloro-2-oxo-2H-chromene-3-sulfonamideHCID 10434323N-(4-bromophenyl)-8-bromo-2-oxo-2H-chromene-3-sulfonamideHCID 115088756-chloro-N-(4-methoxyphenyl)-2-oxo-2H-chromene-3-sulfonamideHCID 11632918N-(4-Bromophenyl)-6-methoxy-2-oxo-2H-chromene-3-sulfonamideHCID 11646267N-(3-Amino-4-fluorophenyl)-6-methoxy-2-oxo-2H-chromene-3-sulfonamideHCID 11667998N-(3-amino-4-fluorophenyl)-8-ethoxy-2-oxo-2H-chromene-3-sulfonamideHCID 117036296-chloro-N-(3-hydroxy-4-methoxyphenyl)-2-oxo-2H-chromene-3-sulfonamideHCID 443933958-ethoxy-N-(4-methoxyphenyl)-2-oxo-2H-chromene-3-sulfonamide2 回

生成物 1

HCID 116472096-bromo-N-(4-methoxyphenyl)-2-oxo-2H-chromene-3-sulfonamide

実験手順

6-chloro-N-(4-methoxyphenyl)-2-oxo-2H-chromene-3-sulfonamide; 8-ethoxy-N-(4-methoxyphenyl)-2-oxo-2H-chromene-3-sulfonamide; 6-chloro-N-(3-hydroxy-4-methoxyphenyl)-2-oxo-2H-chromene-3-sulfonamide; N-(3-amino-4-fluorophenyl)-8-ethoxy-2-oxo-2H-chromene-3-sulfonamide; N-(3-amino-4-fluorophenyl)-6-methoxy-2-oxo-2H-chromene-3-sulfonamide; N-(4-bromophenyl)-6-methoxy-2-oxo-2H-chromene-3-sulfonamide; 8-ethoxy-N-(4-methoxyphenyl)-2-oxo-2H-chromene-3-sulfonamide; N-(4-bromophenyl)-8-chloro-2-oxo-2H-chromene-3-sulfonamide; N-(4-bromophenyl)-8-bromo-2-oxo-2H-chromene-3- sulfonamide; mixtures thereof; and salts thereof.

出典と根拠

ORDレコード
ord-af119e5a5ed44865af0731d844878cd1
出典データセット
uspto-grants-2012_03
特許番号
US08143428B2

反応ノート

読み込み中…