Pyridinium hydrochloride → 4-(3,5-Dinitrophenyl)-9-hydroxypyrrolo[3,4-c]carbazole-1,3(2H,6H)-dione

HRID 11045

反応式

HRID 11045 の反応式
[N+:1]([C:4]1[CH:5]=[C:6]([C:13]2[C:25]3[C:26](=[O:30])[NH:27][C:28](=[O:29])[C:24]=3[C:23]3[C:22]4[CH:21]=[C:20]([O:31]C)[CH:19]=[CH:18][C:17]=4[NH:16][C:15]=3[CH:14]=2)[CH:7]=[C:8]([N+:10]([O-:12])=[O:11])[CH:9]=1)([O-:3])=[O:2].Cl.[NH+]1C=CC=CC=1>>[N+:10]([C:8]1[CH:7]=[C:6]([C:13]2[C:25]3[C:26](=[O:30])[NH:27][C:28](=[O:29])[C:24]=3[C:23]3[C:22]4[CH:21]=[C:20]([OH:31])[CH:19]=[CH:18][C:17]=4[NH:16][C:15]=3[CH:14]=2)[CH:5]=[C:4]([N+:1]([O-:3])=[O:2])[CH:9]=1)([O-:12])=[O:11]

参加物

3

反応物 2

HCID 21584435Pyridinium hydrochlorideHCID 867601914-(3,5-dinitrophenyl)-9-methoxypyrrolo[3,4-c]carbazole-1,3(2H,6H)-dione

生成物 1

HCID 867601924-(3,5-Dinitrophenyl)-9-hydroxypyrrolo[3,4-c]carbazole-1,3(2H,6H)-dione収率 57%

実験手順

The reaction of 4-(3,5-dinitrophenyl)-9-methoxypyrrolo[3,4-c]carbazole-1,3(2H,6H)-dione (V; Ar=3,5-dinitrophenyl, R10═H) (42) prepared as described in example 48 with pyridinium hydrochloride according to the proceedure described in example 81 gave 4-(3,5-Dinitrophenyl)-9-hydroxypyrrolo[3,4-c]carbazole-1,3(2H,6H)-dione (V; Ar=3,5-dinitrophenyl, R10═H) (43) in a 57% yield as an orange powder, mp>330° C. 1H NMR δ [(CD3)2SO] 11.94 (br s, 1H), 11.18 (br s, 1H), 9.32 (br s, 1H), 8.91 (s, 3H), 8.35 (d, J=2.3 Hz, 1H), 7.83 (s, 1H), 7.49 (d, J=8.7 Hz, 1H), 7.11 (dd, J=8.7, 2.3 Hz, 1H).

後処理

  1. customprepared

出典と根拠

ORDレコード
ord-9646ed85d1e945ff98b8b534569f0755
出典データセット
uspto-grants-2006_08
特許番号
US07094798B1

関連ノート

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