2,2',4'-Trichloroacetophenone → HCID 178448900、化合物
反応式
[Cl:1][C:2]1[CH:11]=[C:10]([Cl:12])[CH:9]=[CH:8][C:3]=1[C:4](=O)[CH2:5]Cl.[CH2:13]([NH:17][C:18](=[S:21])[NH:19][NH2:20])[CH2:14][CH2:15][CH3:16]>CO>[ClH:1].[CH2:13]([NH:17][C:18]1[S:21][CH2:5][C:4]([C:3]2[CH:8]=[CH:9][C:10]([Cl:12])=[CH:11][C:2]=2[Cl:1])=[N:20][N:19]=1)[CH2:14][CH2:15][CH3:16]参加物
4
実験手順
4.47 g of 2,4-dichlorophenacyl chloride and 2.66 g of 4-n-butyl-thiosemicarbazide are reacted under the conditions of Example 2 in 150 ml of methanol. The solid obtained is recrystallized from methanol/ethyl acetate, producing 3.98 g of N-butyl-5-(2,4-dichlorophenyl)-6H-1,3,4-thiadiazin-2-amine monohydrochloride. m.p. 180°-182° C.
後処理
- customThe solid obtained
- customis recrystallized from methanol/ethyl acetate
出典と根拠
- ORDレコード
- ord-cd15bdad60d046bf9f7ed4552e5c59aa
- 出典データセット
- uspto-grants-1982_01
- 特許番号
- US04309426
反応ノート
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