化工社化工社 化学情報印刷レポート · 研究参考用
Sodium Iodide → 5-(N,N-Dimethylthiocarbamoyl)thio-4-methyl-2-phenyl-4-isothiazolin-3-one
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Sodium Iodide | HCID 5238 | — |
| 反応物 | Dimethyldithiocarbamic acid | HCID 6599 | — |
| 反応物 | Sodium | HCID 5360545 | — |
| 反応物 | 5-chloro-4-methyl-2-phenylisothiazol-3(2H)-one | HCID 19876167 | — |
| 溶媒 | Ethanol | HCID 702 | — |
| 生成物 | 5-(N,N-Dimethylthiocarbamoyl)thio-4-methyl-2-phenyl-4-isothiazolin-3-one | HCID 12852728 | — |
反応手順
To a solution of 4.51 g. (0.02 mole) of 5-chloro-4-methyl-2-phenyl-4-isothiazolin-3-one in 30 ml of warm ethanol was added a solution of 3.58 g. (0.02 mole) of N,N-dimethyldithiocarbamic acid, sodium salt dihydrate in 20 ml of ethanol followed by 0.1 g. of sodium iodide. The mixture was stirred several hours, cooled and filtered. The solid was triturated with water and dried to give 5.3 g. (88%) of the named product, mp 158°-160°.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04310590 |
| 出典データセット | uspto-grants-1982_01 |
| ORD ID | ord-14fd87cf8fe5449984c02e859ec68e5d |
| 出典メモ | uspto-grants-1982_01 |