Dimethylformamide diethylacetal → 6-chloro-2,3-dihydro-3-dimethylaminomethylene-4H-1-benzothiopyran-4-one
反応式
[Cl:1][C:2]1[CH:3]=[C:4]2[C:9](=[CH:10][CH:11]=1)[S:8][CH2:7][CH2:6][C:5]2=[O:12].C(O[CH:16](OCC)[N:17]([CH3:19])[CH3:18])C>>[Cl:1][C:2]1[CH:3]=[C:4]2[C:9]([S:8][CH2:7][C:6](=[CH:16][N:17]([CH3:19])[CH3:18])[C:5]2=[O:12])=[CH:10][CH:11]=1参加物
3
実験手順
The 7-chloro-3,4-dihydro-2-(dimethylaminomethylene)-4-thia-1(2H)-naphthalenone starting material was prepared from 6-chloro-thiochroman-4-one (3.97 g, 20 mmol) and N,N-dimethylformamide diethyl acetal (20 ml, 80 mmol) to give the desired product as yellow crystals (4.38 g) m.p. 127-128°. MS (ES+) 256 (MH+, 37Cl, 33%), 254 (MH+, 35Cl, 100%).
出典と根拠
- ORDレコード
- ord-054cac8a2b6645f68766c805e330681a
- 出典データセット
- uspto-grants-2000_05
- 特許番号
- US06057329
反応ノート
読み込み中…