N-(3-cyanomethoxyphenyl)methanesulfonamide → N-(3-chloro-5-cyanomethyl-2-methylphenyl) methanesulfonamide
反応式
[NH2:1][C:2]1[CH:3]=[C:4]([CH2:10][C:11]#[N:12])[CH:5]=[C:6]([Cl:9])[C:7]=1[CH3:8].C(COC1C=C(N[S:24]([CH3:27])(=[O:26])=[O:25])C=CC=1)#N.NC1C=C(C=CC=1)OCC#N>>[Cl:9][C:6]1[C:7]([CH3:8])=[C:2]([NH:1][S:24]([CH3:27])(=[O:26])=[O:25])[CH:3]=[C:4]([CH2:10][C:11]#[N:12])[CH:5]=1参加物
4
実験手順
N-(3-chloro-5-cyanomethyl-2-methylphenyl) methanesulfonamide was prepared from (3-amino-5-chloro-4-methylphenyl) acetonitrile in a manner similar to that described in Example 1 for the preparation of N-(3-cyanomethoxyphenyl)-methanesulfonamide from (3-aminophenoxy)-acetonitrile.
出典と根拠
- ORDレコード
- ord-a2c6a46cfcde4a0e9df01dc3b8088c77
- 出典データセット
- uspto-grants-2000_05
- 特許番号
- US06057349
反応ノート
読み込み中…