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Methanol → methyl (2S)-4-methyl-2-(methylamino)pentanoate
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Methanol | HCID 887 | — |
| 反応物 | 1,4-Dioxane | HCID 31275 | — |
| 反応物 | N-Methylleucine | HCID 2777993 | — |
| 溶媒 | Hydrochloric Acid | HCID 313 | — |
| 生成物 | methyl (2S)-4-methyl-2-(methylamino)pentanoate | HCID 10921446 | 100% |
反応手順
N-methyl-L-leucine (1.3 g, 8.95 mmol) was dissolved in 4M HCl, 1,4-dioxane (10 mL) and methanol (10 mL). The solution was stirred overnight at room temperature, then concentrated to afford the title compound as a white solid (100%). MS (ESI): 160.0 (M+H)+.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US06057362 |
| 出典データセット | uspto-grants-2000_05 |
| ORD ID | ord-a4e939e82e59463f9d46a2aad4b488ab |
| 出典メモ | uspto-grants-2000_05 |