2-Thiophenemethanol → 1-(2-Butenyl)-2,3-dimethyl-7-(2-thienylmethyloxy)pyrrolo[2,3-d]pyridazine

HRID 1107758

反応式

HRID 1107758 の反応式
[CH2:1]([N:5]1[C:9]2=[C:10](Cl)[N:11]=[N:12][CH:13]=[C:8]2[C:7]([CH3:15])=[C:6]1[CH3:16])[CH:2]=[CH:3][CH3:4].[S:17]1[CH:21]=[CH:20][CH:19]=[C:18]1[CH2:22][OH:23]>>[CH2:1]([N:5]1[C:9]2=[C:10]([O:23][CH2:22][C:18]3[S:17][CH:21]=[CH:20][CH:19]=3)[N:11]=[N:12][CH:13]=[C:8]2[C:7]([CH3:15])=[C:6]1[CH3:16])[CH:2]=[CH:3][CH3:4]

参加物

3

反応物 2

HCID 694672-ThiophenemethanolHCID 537196241-(2-Butenyl)-7-chloro-2,3-dimethylpyrrolo[2,3-d]pyridazine

生成物 1

HCID 544657941-(2-Butenyl)-2,3-dimethyl-7-(2-thienylmethyloxy)pyrrolo[2,3-d]pyridazine収率 20.6%

実験手順

The title compound (cis/trans=20/80) was prepared as a grayish white powder in 20.6% yield in a similar procedure to that described in Example 1 by using 1-(2-butenyl)-7-chloro-2,3-dimethylpyrrolo[2,3-d]pyridazine (cis/trans=20/80) and 2-thiophenemethanol.

出典と根拠

ORDレコード
ord-c0a3d2e330cf4a70a473048bfac85874
出典データセット
uspto-grants-2000_05
特許番号
US06063782

関連ノート

読み込み中…