3-Pyridinemethanol → 1-(2-Butenyl)-2,3-dimethyl-7-(3-pyridylmethyloxy)pyrrolo[2,3-d]pyridazine

HRID 1107762

反応式

HRID 1107762 の反応式
[CH2:1]([N:5]1[C:9]2=[C:10](Cl)[N:11]=[N:12][CH:13]=[C:8]2[C:7]([CH3:15])=[C:6]1[CH3:16])[CH:2]=[CH:3][CH3:4].[N:17]1[CH:22]=[CH:21][CH:20]=[C:19]([CH2:23][OH:24])[CH:18]=1>>[CH2:1]([N:5]1[C:9]2=[C:10]([O:24][CH2:23][C:19]3[CH:18]=[N:17][CH:22]=[CH:21][CH:20]=3)[N:11]=[N:12][CH:13]=[C:8]2[C:7]([CH3:15])=[C:6]1[CH3:16])[CH:2]=[CH:3][CH3:4]

参加物

3

反応物 2

HCID 75103-PyridinemethanolHCID 537196241-(2-Butenyl)-7-chloro-2,3-dimethylpyrrolo[2,3-d]pyridazine

生成物 1

HCID 542747031-(2-Butenyl)-2,3-dimethyl-7-(3-pyridylmethyloxy)pyrrolo[2,3-d]pyridazine収率 45.9%

実験手順

The title compound (cis/trans=22/78) was prepared as a pale yellow powder in 45.9% yield in a similar procedure to that described in Example 1 by using 1-(2-butenyl)-7-chloro-2,3-dimethylpyrrolo[2,3-d]pyridazine (cis/trans=20/80) and 3-pyridinemethanol.

出典と根拠

ORDレコード
ord-c77aeee2fd294e5ca0504fb5d230a2c9
出典データセット
uspto-grants-2000_05
特許番号
US06063782

関連ノート

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