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HRID 1107785作成日:2026年10月26日

4-Fluorobenzylic alcohol → 7-[(4-Fluorophenyl)methoxy]-2,3-dimethyl-1-[(2-methylcyclopropyl)methyl]pyrrolo[2,3-d]pyridazine

https://huagongshe.com/reaction/1107785

反応式

関与物質

役割名称HCID仕込み量
反応物4-Fluorobenzylic alcoholHCID 68022—
反応物7-Chloro-2,3-dimethyl-1-(2-methylcyclopropylmethyl)pyrrolo[2,3-d]pyridazineHCID 22719650—
生成物7-[(4-Fluorophenyl)methoxy]-2,3-dimethyl-1-[(2-methylcyclopropyl)methyl]pyrrolo[2,3-d]pyridazineHCID 467291691.6%

反応手順

The title compound (trans) was prepared as a white powder in 91.60% yield in a similar procedure to that described in Example 1 by using 7-chloro-2,3-dimethyl-1-(2-methylcyclopropylmethyl)pyrrolo[2,3-d]pyridazine and 4-fluorobenzyl alcohol.

情報源と証拠

DOI10.6084/m9.figshare.5104873.v1
特許番号US06063782
出典データセットuspto-grants-2000_05
ORD IDord-68a117a6c4cd4aaea82f089b4e0a819e
出典メモuspto-grants-2000_05