1,1,1-Trifluoro-2-iodoethane → Methyl 3-formyl-4,5-dimethyl-1-(2,2,2-trifluoroethyl)pyrrole-2-carboxylate

反応式

[CH:1]([C:3]1[C:7]([CH3:8])=[C:6]([CH3:9])[NH:5][C:4]=1[C:10]([O:12][CH3:13])=[O:11])=[O:2].[F:14][C:15]([F:19])([F:18])[CH2:16]I>>[CH:1]([C:3]1[C:7]([CH3:8])=[C:6]([CH3:9])[N:5]([CH2:16][C:15]([F:19])([F:18])[F:14])[C:4]=1[C:10]([O:12][CH3:13])=[O:11])=[O:2]

参加物

反応物 2

HCID 677091,1,1-Trifluoro-2-iodoethane

HCID 10773740Methyl 3-formyl-4,5-dimethyl-1H-pyrrole-2-carboxylate

生成物 1

HCID 18785628Methyl 3-formyl-4,5-dimethyl-1-(2,2,2-trifluoroethyl)pyrrole-2-carboxylate

実験手順

The title compound was prepared as pale brown crystals in 5.5% yeild in a similar procedure to that described in Referential Example 9 by using methyl 3-formyl-4,5-dimethylpyrrole-2-carboxylate and 1,1,1-trifluoro-2-iodoethane.

出典と根拠

ORDレコード: ord-8aaa2929de4d4918b72a8a0ff2bed6f2
出典データセット: uspto-grants-2000_05
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US06063782

反応ノート

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