化工社化工社 化学情報印刷レポート · 研究参考用
4-Cyano-4-(3-hydroxyphenyl)-3,4,5,6-tetrahydro-2H-pyran → 4-Cyano-4-[3-[4-(2-methylimidazol-1-yl)benzyloxy]phenyl]-3,4,5,6-tetrahydro-2H-pyran
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 4-Cyano-4-(3-hydroxyphenyl)-3,4,5,6-tetrahydro-2H-pyran | HCID 11287160 | — |
| 反応物 | 1-(4-Chloromethylphenyl)-2-methyl-1H-imidazole | HCID 14998821 | — |
| 生成物 | 4-Cyano-4-[3-[4-(2-methylimidazol-1-yl)benzyloxy]phenyl]-3,4,5,6-tetrahydro-2H-pyran | HCID 11349311 | 38% |
反応手順
4-Cyano-4-(3-hydroxyphenyl)-3,4,5,6-tetrahydro-2H-pyran was reacted with 4-(2-methylimidazol-1-yl)benzylchloride to give the titled compound in 38% yield as colorless needles according to the procedure described in Example 2H.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US06063928 |
| 出典データセット | uspto-grants-2000_05 |
| ORD ID | ord-4ba22721a4784675b2d3480b6f9d5e73 |
| 出典メモ | uspto-grants-2000_05 |