1,5-Dibromopentane → Ethyl 1-(3-benzyloxy-5-fluorophenyl)cyclohexane-1-carboxylate

反応式

[CH2:1]([O:8][C:9]1[CH:10]=[C:11]([CH2:16][C:17]([O:19][CH2:20][CH3:21])=[O:18])[CH:12]=[C:13]([F:15])[CH:14]=1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.Br[CH2:23][CH2:24][CH2:25][CH2:26][CH2:27]Br>>[CH2:1]([O:8][C:9]1[CH:10]=[C:11]([C:16]2([C:17]([O:19][CH2:20][CH3:21])=[O:18])[CH2:27][CH2:26][CH2:25][CH2:24][CH2:23]2)[CH:12]=[C:13]([F:15])[CH:14]=1)[C:2]1[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=1

参加物

反応物 2

HCID 81001,5-Dibromopentane

HCID 18786372Ethyl 3-benzyloxy-5-fluorophenylacetate

生成物 1

HCID 18786379Ethyl 1-(3-benzyloxy-5-fluorophenyl)cyclohexane-1-carboxylate

実験手順

The titled compound was prepared from ethyl 3-benzyloxy-5-fluorophenylacetate according to the procedure described in Example 2F except that 1,5-dibromopentane was used in place of bis(2-chloroethyl) ether.

出典と根拠

ORDレコード: ord-81de5f774a444326bc2e0643f073ad93
出典データセット: uspto-grants-2000_05
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US06063928

反応ノート

読み込み中…